Match!

Importance of proper scaling of aerobic power when relating to cardiometabolic risk factors in children

Published on Sep 1, 2011in Annals of Human Biology1.588
· DOI :10.3109/03014460.2011.598561
Robert G. McMurray46
Estimated H-index: 46
(UNC: University of North Carolina at Chapel Hill),
Peter A. Hosick5
Estimated H-index: 5
(UNC: University of North Carolina at Chapel Hill),
Anna Bugge20
Estimated H-index: 20
(University of Southern Denmark)
Abstract
Background: The relationship between cardiometabolic risk factors (CMRF) and aerobic power (VO2max) scaled as mL O2 per kilogram body mass is controversial because mass includes both fat and fat-free mass, and fat mass is independently associated with the CMRF.Aim: To examine common units used to scale VO2max and their relationships to mean blood pressure (MBP), total cholesterol (TC), HDL cholesterol, triglycerides (TG), insulin resistance (HOMA-IR) and cumulative risk score (z-score).Subjects: 1784, 8–18 year-old youths, 938 girls and 886 boys.Methods: Fasting blood samples were obtained. VO2max was estimated in mL/min from cycle ergometry and scaled to body mass (kg), fat free mass (kgFFM), body surface area (m2), height (cm) and allometric (mL/kg0.67/min).Results: Unadjusted correlations between CMRF and many of the scaled VO2max units were significant (p < 0.0001), especially for MBP, HOMA-IR, HDL and z-score, with lower correlations for TC and TG. After adjusting for ancestry, sex, height and body f...
  • References (43)
  • Citations (20)
📖 Papers frequently viewed together
40 Citations
1,047 Citations
6 Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
References43
Newest
#1Magnus Dencker (Lund University)H-Index: 20
#2Per Wollmer (Lund University)H-Index: 39
Last. Ola Thorsson (Lund University)H-Index: 23
view all 6 authors...
9 CitationsSource
#1Silvia Sookoian (UBA: University of Buenos Aires)H-Index: 37
#2Carlos J. Pirola (UBA: University of Buenos Aires)H-Index: 41
The metabolic syndrome (MS) constitutes a combination of underlying risk factors for an adverse outcome, cardiovascular disease. Thus, the clinical behavior of the MS can be regarded as a whole. Nevertheless, from a pathogenic point of view, understanding of the underlying mechanisms of each MS intermediate phenotype is far beyond their understanding as an integrative process. Systems biology introduces a new concept for revealing the pathogenesis of human disorders and suggests the presence of ...
54 CitationsSource
#1Magnus Dencker (University of Southern Denmark)H-Index: 20
#2Anna Bugge (University of Southern Denmark)H-Index: 20
Last. Lars Bo Andersen (University of Southern Denmark)H-Index: 64
view all 5 authors...
Aim: The purpose of this study was to investigate the relationship between maximum oxygen uptake (VO2PEAK) and body fat in young children on a population-based level. Methods: Participants were 586 children (311 boys and 275 girls) aged 6.8 +/- 0.4 years, recruited from a population-based cohort. VO2PEAK was measured by indirect calorimetry during a maximal exercise test. Percent body fat (BF%) was estimated from skinfold measurements. Results: Significant relationships existed between BF% and a...
10 CitationsSource
#1Katie Suriano (Telethon Institute for Child Health Research)H-Index: 3
#2J. CurranH-Index: 2
Last. Elizabeth A. Davis (Telethon Institute for Child Health Research)H-Index: 44
view all 5 authors...
Objectives To investigate the relationships between cardiorespiratory fitness and adiposity among young children, and their influence on a comprehensive cardiovascular risk profile. Study design The sample included 95 healthy weight, 54 overweight, and 31 obese children (n = 180, 10.9 ± 2.1 years). All children had a medical assessment that included a physical examination and fasting investigations including glycated hemoglobin, total cholesterol, high-density lipoprotein, low-density lipoprotei...
40 CitationsSource
#1Russell Jago (UoB: University of Bristol)H-Index: 49
#2Kimberly L. Drews (GW: George Washington University)H-Index: 11
Last. Zenong Yin (UTSA: University of Texas at San Antonio)H-Index: 1
view all 11 authors...
Data from the 1999–2002 US National Health and Nutrition Examination Survey indicated that less than one-third of 12- to 19-yr-old adolescents in the United States met fitness recommendations (28). Low aerobic fitness levels have been associated with increased risk for cardiovascular diseases (21) and diabetes mellitus among adults (23). In children and adolescents, low aerobic fitness has also been associated with cardiometabolic (5) risk factors (large waist circumference, high blood pressure,...
33 CitationsSource
#1Robert G. McMurray (UNC: University of North Carolina at Chapel Hill)H-Index: 46
#2Lars Bo Andersen (Norwegian School of Sport Sciences)H-Index: 64
The metabolic syndrome (MetS) is a clustering of dyslipidemia, hypertension, glucose intolerance, and central obesity or waist circumference that places individuals at high risk for developing cardiovascular or heart disease. Although first characterized in adults, it has been found in children, but the definition of MetS in children is still controversial. Although MetS is most closely associated with obesity in children, 2 factors believed to affect MetS are physical activity (PA) and aerobic ...
43 CitationsSource
#1Tina Tanha (Lund University)H-Index: 4
#2Magnus Dencker (Lund University)H-Index: 20
Last. Ola Thorsson (Lund University)H-Index: 23
view all 6 authors...
2 Citations
#1Adrian J. Cameron (Monash University)H-Index: 37
#2Edward J. Boyko (Baker IDI Heart and Diabetes Institute)H-Index: 73
Last. Jonathan E. Shaw (Baker IDI Heart and Diabetes Institute)H-Index: 96
view all 9 authors...
Evidence from epidemiologic studies that central obesity precedes future metabolic change and does not occur concurrently with the appearance of the blood pressure, glucose, and lipid abnormalities ...
88 CitationsSource
#1Jose Peralta-Huertas (Brock University)H-Index: 3
#2Kristina Livingstone (Brock University)H-Index: 3
Last. Deborah O’LearyD. O’Leary (Brock University)H-Index: 1
view all 5 authors...
This study examined cardiac and arterial differences between overweight and normal-weight preadolescent children. Twenty children (10.2 ± 0.4 years of age) classified as overweight, on the basis of age-appropriate body mass index (BMI) cutoffs, were compared with 43 normal-weight controls. Height, mass, and body surface area were measured. Relative body fat and lean body mass were estimated from skinfold thickness. Each child’s weekly physical activity metabolic equivalent (PAME) was calculated ...
7 CitationsSource
#1Robert G. McMurray (UNC: University of North Carolina at Chapel Hill)H-Index: 46
#2Shrikant I. Bangdiwala (UNC: University of North Carolina at Chapel Hill)H-Index: 61
Last. Leila D. Amorim (UNC: University of North Carolina at Chapel Hill)H-Index: 16
view all 4 authors...
Purpose Metabolic syndrome (MS) is a clustering of cardiovascular disease risk factors that identifies individuals with the highest risk for heart disease. Two factors that may influence the MS are physical activity and aerobic fitness. This study determined if adolescent with the MS had low levels of aerobic fitness and physical activity as children.
63 CitationsSource
Cited By20
Newest
#1Giovani dos Santos Cunha (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 11
#2Gabriela Tomedi Leites (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 2
Source
#1Eivind AadlandH-Index: 12
#2Sigmund A. Anderssen (Norwegian School of Sport Sciences)H-Index: 48
Last. Jostein Steene-Johannessen (Norwegian School of Sport Sciences)H-Index: 22
view all 6 authors...
This is the peer reviewed (post-print) version of the following article: Aadland, E., Anderssen, S. A., Andersen, L. B., Resaland, G. K., Kolle, E., & Steene-Johannessen, J. (2019). Aerobic fitness thresholds to define poor cardiometabolic health in children and youth. Scandinavian Journal of Medicine & Science in Sports, 29(2), 240-250, which has been published in final form at https://onlinelibrary.wiley.com/doi/full/10.1111/sms.13330. This article may be used for non-commercial purposes in ac...
3 CitationsSource
#1Andrew O. Agbaje (University of Eastern Finland)H-Index: 1
#2Eero A. Haapala (University of Jyväskylä)H-Index: 10
Last. Timo A. Lakka (University of Eastern Finland)H-Index: 80
view all 9 authors...
3 CitationsSource
#1M. Kamel (McMaster University)H-Index: 1
#2Brendan T. Smith (U of T: University of Toronto)H-Index: 4
Last. Laura N. Anderson (McMaster University)H-Index: 14
view all 6 authors...
1 CitationsSource
#1Eero A. Haapala (University of Jyväskylä)H-Index: 10
#2Jari A. Laukkanen (University of Jyväskylä)H-Index: 36
Last. Taija Finni (University of Jyväskylä)H-Index: 32
view all 5 authors...
Purpose To investigate the associations of peak oxygen uptake (\(\dot {V}{{\text{O}}_{2{\text{peak}}}}\)) and \(\dot {V}{{\text{O}}_2}\) at ventilatory threshold (\(\dot {V}{{\text{O}}_2}\) at VT) with arterial stiffness in adolescents.
1 CitationsSource
Last. Erlingur JohannssonH-Index: 18
view all 5 authors...
The Icelandic Centre for Research (RANNIS) funded this study, along with the Ministry of Education, Science and Culture, and The Icelandic Primary Health Care Research Fund. The authors have no conflicts of interest.
Source
#1Sakari Jukarainen (UH: University of Helsinki)H-Index: 4
#2René Holst (University of Southern Denmark)H-Index: 20
Last. Kirsi H. Pietiläinen (UH: University of Helsinki)H-Index: 49
view all 12 authors...
The joint effects of cardiorespiratory fitness (CRF) and body composition on metabolic health are not well known.To examine the associations of CRF, fat-free mass index (FFMI), and fat mass index (FMI) with metabolic health in individual twins and controlling for genetic and shared environmental effects by studying monozygotic intrapair differences.Two cross-sectional samples of healthy adult monozygotic and dizygotic twins were drawn from population-based Danish and Finnish national twin regist...
4 CitationsSource
#1Emily Hill Guseman (UW: University of Wyoming)H-Index: 3
#2Samuel P. Cauffman (UAB: University of Alabama at Birmingham)
Last. William Stratbucker (Spectrum Health)H-Index: 5
view all 6 authors...
Abstract Background: Both cardiorespiratory fitness (CRF) and measures of muscular fitness are associated with metabolic syndrome in adults. However, limited information exists about these relationships in youth with severe obesity who are at increased risk of metabolic dysfunction. The purpose of this study was to examine the relationship between fitness and metabolic health in treatment-seeking youth with obesity. Methods: Data for this analysis were collected at the time of baseline visits at...
Source
#1Sigurbjörn Á. Arngrímsson (University of Iceland)H-Index: 18
#2Anna SigríĐur Ólafsdóttir (University of Iceland)H-Index: 1
Objectives To investigate the total, direct and mediated (by fatness) association of physical activity (PA) with fitness. Methods Body fat percentage (%Fat), maximal oxygen uptake (VO2max) and PA were measured directly in 18-year-olds (n=202) and their association analyzed with a linear regression-based mediation analysis after controlling for sex. Results The total association between PA and VO2max was significant (c=0.66, P<0.001) and was significantly mediated by %Fat (ab=0.25, 95% CI: 0.04–0...
4 CitationsSource
#1Elvar Smari Sævarsson (University of Iceland)H-Index: 2
#2Kristjan Thor Magnusson (University of Iceland)H-Index: 4
Last. Sigurbjörn Á. Arngrímsson (University of Iceland)H-Index: 18
view all 5 authors...
AbstractBackground: The strong relation between cardiorespiratory fitness (CRF) and adiposity renders their independent associations to metabolic risk factors difficult to ascertain.Aim: To determine the associations of CRF and CRF relative to fat-free mass (CRFFFM) to total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides, glucose, insulin and homeostasis model assessment (HOMA) and distinguish these relations from the association to adiposity.Subjects and methods: ...
2 CitationsSource