Why size matters – balancing mitochondrial dynamics in Alzheimer's disease
Abstract
Once perceived as solitary structures, mitochondria are now recognized as highly dynamic, interconnected organelles. The tight control of their fusion and fission, a process termed 'mitochondrial dynamics', is crucial for neurons, given their unique architecture and special energy and calcium-buffering requirements at the synapse. Interestingly, in Alzheimer's disease (AD), a condition initiated at the synapse, mitochondrial dynamics are...
Paper Details
Title
Why size matters – balancing mitochondrial dynamics in Alzheimer's disease
Published Date
Jun 1, 2013
Journal
Volume
36
Issue
6
Pages
325 - 335
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