Optimal spliced alignments of short sequence reads
Abstract
Motivation: Next generation sequencing technologies open exciting new possibilities for genome and transcriptome sequencing. While reads produced by these technologies are relatively short and error prone compared to the Sanger method their throughput is several magnitudes higher. To utilize such reads for transcriptome sequencing and gene structure identification, one needs to be able to accurately align the sequence reads over intron...
Paper Details
Title
Optimal spliced alignments of short sequence reads
Published Date
Oct 1, 2008
Journal
Volume
9
Issue
S10
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Notes
History