The role of mast cells in allergic inflammation
Abstract
The histochemical characteristics of human basophils and tissue mast cells were described over a century ago by Paul Ehrlich. When mast cells are activated by an allergen that binds to serum IgE attached to their FcɛRI receptors, they release cytokines, eicosanoids and their secretory granules. Mast cells are now thought to exert critical proinflammatory functions, as well as potential immunoregulatory roles, in various immune disorders through...
Paper Details
Title
The role of mast cells in allergic inflammation
Published Date
Jan 1, 2012
Journal
Volume
106
Issue
1
Pages
9 - 14
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Notes
History