Adalimumab in active ulcerative colitis: A “real-life” observational study

The effectiveness of adalimumab in the treatment of ulcerative colitis is under debate. Although controlled trials have shown that adalimumab is significantly better than placebo, the absolute clinical benefit is modest. We report data on the effectiveness of adalimumab in a cohort of ulcerative colitis patients treated in 22 Italian centres.All patients with active disease treated with adalimumab were retrospectively reviewed. Co-primary...