High Fat Diet-Induced Changes in Hepatic Protein Abundance in Mice
Abstract
Nonalcoholic fatty liver disease (NAFLD) is associated with obesity, insulin resistance, type 2 diabetes, and dyslipidemia. The purpose of this study was to identify novel proteins and pathways that contribute to the pathogenesis and complications of NAFLD. C57BL/6J male mice were fed a 60% (HFD) or 10% (LFD) high or low fat diet. HFD induced obesity, hepatic steatosis and insulin resistance (euglycemic clamps, glucose infusion rate: LFD 50.5 ±...
Paper Details
Title
High Fat Diet-Induced Changes in Hepatic Protein Abundance in Mice
Published Date
Jan 1, 2012
Volume
05
Issue
03
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