Age-related changes in fat deposition in mid-thigh muscle in women: relationships with metabolic cardiovascular disease risk factors

OBJECTIVE: To determine if fat deposition within mid-thigh muscle, represented by low density lean tissue density, is associated with age, low physical fitness, hyperleptinemia, hyperinsulinemia and dyslipidemia in women. SUBJECTS: Seventy-two women aged 18–69 y with a wide range of total body fat (10–55%) and maximal aerobic capacity (VO2max: 17–61 ml/kg−1/min−1). MEASUREMENTS: Mid-thigh muscle, mid-thigh fat, low density lean tissue,...