Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease

Volume: 93, Issue: 6, Pages: 837 - 845
Published: Jan 29, 2013
Abstract
Accelerated cardiovascular disease is a frequent complication of CKD. Monocyte-mediated inflammation and adhesion of monocytes to vascular endothelium are key events in atherogenesis. An oral adsorbent, AST-120, retards renal function deterioration by lowering IS, which is known to accumulate in CKD patients. However, the effect of AST-120 on CKD-related monocyte activation is unknown. We aimed to determine whether AST-120 improves...
Paper Details
Title
Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease
Published Date
Jan 29, 2013
Volume
93
Issue
6
Pages
837 - 845
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