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Fruit and vegetable consumption and all-cause mortality: a dose-response analysis

Published on Aug 1, 2013in The American Journal of Clinical Nutrition6.57
· DOI :10.3945/ajcn.112.056119
Andrea Bellavia14
Estimated H-index: 14
(KI: Karolinska Institutet),
Susanna C. Larsson61
Estimated H-index: 61
(KI: Karolinska Institutet)
+ 2 AuthorsNicola Orsini43
Estimated H-index: 43
(KI: Karolinska Institutet)
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Abstract
Background: The association between fruit and vegetable (FV) consumption and overall mortality has seldom been investigated in large cohort studies. Findings from the few available studies are inconsistent. Objective: The objective was to examine the dose-response relation between FV consumption and mortality, in terms of both time and rate, in a large prospective cohort of Swedish men and women. Design: FV consumption was assessed through a self-administrated questionnaire in a population-based cohort of 71,706 participants (38,221 men and 33,485 women) aged 45–83 y. We performed a dose-response analysis to evaluate 10th survival percentile differences (PDs) by using Laplace regression and estimated HRs by using Cox regression. Results: During 13 y of follow-up, 11,439 deaths (6803 men and 4636 women) occurred in the cohort. In comparison with 5 servings FV/d, a lower consumption was progressively associated with shorter survival and higher mortality rates. Those who never consumed FV lived 3 y shorter (PD: 237 mo; 95% CI: 258, 216 mo) and had a 53% higher mortality rate (HR: 1.53; 95% CI: 1.19, 1.99) than did those who consumed 5 servings FV/d. Consideration of fruit and vegetables separately showed that those who never consumed fruit lived 19 mo shorter (PD: 219 mo; 95% CI: 229, 210 mo) than did those who ate 1 fruit/d. Participants who consumed 3 vegetables/d lived 32 mo longer than did those who never consumed vegetables (PD: 32 mo; 96% CI: 13, 51 mo). Conclusion: FV consumption ,5 servings/d is associated with progressively shorter survival and higher mortality rates. The Swedish Mammography Cohort and the Cohort of Swedish Men were registered at clinicaltrials.gov as NCT01127698 and NCT01127711, respectively. Am J Clin Nutr doi: 10.3945/ajcn.112.056119.
  • References (24)
  • Citations (81)
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References24
Newest
Published on Sep 1, 2012in Epidemiology4.72
Nicola Orsini43
Estimated H-index: 43
,
Alicja Wolk110
Estimated H-index: 110
,
Matteo Bottai44
Estimated H-index: 44
Published on May 1, 2012in Journal of the American Geriatrics Society4.11
Emily J. Nicklett13
Estimated H-index: 13
(UM: University of Michigan),
Richard David Semba1
Estimated H-index: 1
(UPenn: University of Pennsylvania)
+ 6 AuthorsLinda P. Fried117
Estimated H-index: 117
(Columbia University)
DESIGN: Six Cox proportional hazards models examined independent and additive relationships between physical activity, carotenoids, and all-cause mortality. Additional models tested whether physical activity and carotenoids were conjointly related to mortality. Models were adjusted for age, education, and race and ethnicity. SETTING: Baltimore, Maryland. PARTICIPANTS: Seven hundred thirteen women aged 70 to 79 participating in the Women’s Health and Aging Studies. MEASUREMENTS: Total serum carot...
Published on Mar 1, 2011in American Journal of Neuroradiology3.26
Olivier Naggara25
Estimated H-index: 25
,
Jean Raymond35
Estimated H-index: 35
+ 3 AuthorsDouglas G. Altman208
Estimated H-index: 208
SUMMARY: In medical research analyses, continuous variables are often converted into categoric variables by grouping values into ≥2 categories. The simplicity achieved by creating ≥2 artificial groups has a cost: Grouping may create rather than avoid problems. In particular, dichotomization leads to a considerable loss of power and incomplete correction for confounding factors. The use of data-derived “optimal” cut-points can lead to serious bias and should at least be tested on independent obse...
Published on Mar 1, 2011in Nutrition Research2.63
Michelle Shardell36
Estimated H-index: 36
(UMB: University of Maryland, Baltimore),
Dawn E. Alley32
Estimated H-index: 32
(UMB: University of Maryland, Baltimore)
+ 4 AuthorsLuigi Ferruci142
Estimated H-index: 142
(NIH: National Institutes of Health)
Abstract Evidence regarding the health benefits of carotenoids is controversial. Effects of serum carotenoids and their interactions on mortality have not been examined in a representative sample of US adults. The objective was to examine whether serum carotenoid concentrations predict mortality among US adults. The study consisted of adults aged ≥20 years enrolled in the Third National Health and Nutrition Examination Survey, 1988 to 1994, with measured serum carotenoids and mortality follow-up...
Published on Mar 1, 2011in Stata Journal1.80
Nicola Orsini43
Estimated H-index: 43
(KI: Karolinska Institutet),
Sander Greenland104
Estimated H-index: 104
(UCLA: University of California, Los Angeles)
The use of flexible models for the relationship between a quantitative covariate and the response variable can be limited by the difficulty in interpret- ing the regression coefficients. In this article, we present a new postestimation command, xblc, that facilitates tabular and graphical presentation of these relationships. Cubic splines are given special emphasis. We illustrate the command through several worked examples using data from a large study of Swedish men on the relation between phys...
Published on Feb 2, 2011in Journal of the National Cancer Institute10.21
Paolo Boffetta124
Estimated H-index: 124
(Strathclyde Institute of Pharmacy and Biomedical Sciences),
Elisabeth Couto14
Estimated H-index: 14
(IARC: International Agency for Research on Cancer)
+ 49 AuthorsHeiner Boeing108
Estimated H-index: 108
BACKGROUND: It is widely believed that cancer can be prevented by high intake of fruits and vegetables. However, inconsistent results from many studies have not been able to conclusively establish an inverse association between fruit and vegetable intake and overall cancer risk. METHODS: We conducted a prospective analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort to assess relationships between intake of total fruits, total vegetables, and total fruits an...
Published on Aug 1, 2010in Biometrical Journal1.25
Matteo Bottai44
Estimated H-index: 44
(KI: Karolinska Institutet),
Jiajia Zhang19
Estimated H-index: 19
(USC: University of South Carolina)
We consider a regression model where the error term is assumed to follow a type of asymmetric Laplace distribution. We explore its use in the estimation of conditional quantiles of a continuous outcome variable given a set of covariates in the presence of random censoring. Censoring may depend on covariates. Estimation of the regression coefficients is carried out by maximizing a non-differentiable likelihood function. In the scenarios considered in a simulation study, the Laplace estimator show...
Published on Nov 1, 2009in European Journal of Epidemiology6.53
Jonas F. Ludvigsson52
Estimated H-index: 52
(Örebro University),
Petra Otterblad-Olausson2
Estimated H-index: 2
(National Board of Health and Welfare)
+ 1 AuthorsAnders Ekbom98
Estimated H-index: 98
(Karolinska University Hospital)
Swedish health care and national health registers are dependent on the presence of a unique identifier. This paper describes the Swedish personal identity number (PIN) and explores ethical issues of its use in medical research. A ten-digit-PIN is maintained by the National Tax Board for all individuals that have resided in Sweden since 1947. Until January 2008, an estimated 75,638 individuals have changed PIN. The most common reasons for change of PIN are incorrect recording of date of birth or ...
Published on Apr 1, 2009in European Journal of Clinical Nutrition3.11
Joanna Kaluza9
Estimated H-index: 9
,
Niclas Håkansson32
Estimated H-index: 32
+ 1 AuthorsAlicja Wolk110
Estimated H-index: 110
Background/Objectives: To study quality of diet in relation to all-cause mortality, cardiovascular disease (CVD) and cancer mortality. Subjects/Methods: The population-based prospective Cohort of Swedish Men (COSM) included 40 837 men, 45–79 years of age, who filled in a FFQ (96 food items) and were CVD- and cancer-free at baseline. Quality of diet was assessed by Recommended Food Score (RFS) based on 36 items and Non-Recommended Food Score (Non-RFS) based on 16 items. Cox’s proportional hazards...
Published on Sep 1, 2008in European Journal of Nutrition4.45
Fulvio Lauretani42
Estimated H-index: 42
,
Richard D. Semba65
Estimated H-index: 65
(Johns Hopkins University)
+ 6 AuthorsLuigi Ferruci142
Estimated H-index: 142
(NIH: National Institutes of Health)
Background Plasma carotenoids are considered a valid biological marker for fruit and vegetable dietary intake. Recent studies show that low carotenoid levels are associated with a high risk of inflammation, cancer, and cardiovascular disease.
Cited By81
Newest
Published on Jun 11, 2019in International Journal of Public Health
Adája E. Baars (EUR: Erasmus University Rotterdam), Jose R. Rubio-Valverde (EUR: Erasmus University Rotterdam)+ 10 AuthorsChris White7
Estimated H-index: 7
(Office for National Statistics)
Objectives To assess to what extent educational differences in total life expectancy (TLE) and disability-free life expectancy (DFLE) could be reduced by improving fruit and vegetable consumption in ten European countries.
Jitendra Kumar Singh3
Estimated H-index: 3
,
Dilaram Acharya2
Estimated H-index: 2
+ 4 AuthorsKwan Lee4
Estimated H-index: 4
Sufficient fruit and vegetable (FV) consumption has been associated with reduced risks of chronic diseases and adverse health conditions. However, the determinants of insufficient of FV intake among adolescent girls in Nepal have not been determined. This study was undertaken to identify associations between socio-demographic and diet-related factors with insufficient fruit and vegetable consumption among adolescent girls living in rural communities. This community-based, cross-sectional study w...
Published on May 1, 2019in American Journal of Lifestyle Medicine
Lisa Offringa2
Estimated H-index: 2
(Stanford University),
Michael V. Stanton9
Estimated H-index: 9
(Stanford University)
+ 1 AuthorsChristopher D. Gardner35
Estimated H-index: 35
(Stanford University)
Both vegetable and fruit consumption contribute to wellness and disease prevention. Most dietary health messages promote both together and position the word “fruits” before “vegetables.” We examined the word order of the commonly used phrase “fruits and vegetables” through linguistics, psychology, botany, nutrition, health outcomes, and current US intake to determine if the common word order best presents these two foods in health messaging. By comparing the 10 most commonly consumed vegetables ...
Yuxia Ouyang (PSU: Pennsylvania State University), Amit Sharma10
Estimated H-index: 10
(PSU: Pennsylvania State University)
Purpose The purpose of this study was to investigate the preference of health-warning message labeling in an eating-away-from-home context. The authors assessed individuals’ preference valuation of such messaging from a dual – consumer and citizen – perspective and with associated expected risk reduction (RR) level. Design/methodology/approach In an online stated choice experiment on Amazon’s Mechanical Turk (N = 658), participants were asked to provide willingness to pay (WTP) preferences for h...
Published on Feb 4, 2019in British Food Journal1.72
Daniele Eckert Matzembacher1
Estimated H-index: 1
(UFRGS: Universidade Federal do Rio Grande do Sul),
Fabio Bittencourt Meira1
Estimated H-index: 1
(UFRGS: Universidade Federal do Rio Grande do Sul)
Purpose The purpose of this paper is to investigate how sustainability integrates the business strategy of Brazilian community supported agriculture (CSA) initiatives, and to understand the social, environmental and economic benefits to producers and consumers. Design/methodology/approach A case study was carried out through participant observation, using the techniques of ethnography, in addition to in-depth interviews and access to secondary data. Follow-up was carried out over two years and s...
Published on Feb 1, 2019in Clinical Nutrition6.40
Saho Abe (Tohoku University), Shu Zhang4
Estimated H-index: 4
(Tohoku University)
+ 3 AuthorsIchiro Tsuji1
Estimated H-index: 1
(Tohoku University)
Summary Background & aims Although it has been suggested that the Japanese diet contributes to the longevity of the Japanese population, no study has examined the association between the Japanese diet and survival time. The present study investigated the association between the Japanese diet and survival time. Methods We analyzed 20-year follow-up data from a cohort study of 14,764 Japanese men and women aged 40–79 years. At the baseline survey in 1994, we collected dietary information using a v...
Resume But de l’etude En prevention primaire des maladies cardiovasculaires, l’education therapeutique du patient aide a la mise en place d’une hygiene de vie protectrice, dans un contexte societal ou les facteurs de risque abondent. Patients et methodes L’education therapeutique du patient propose aux personnes desireuses de preserver leur sante cardiovasculaire un programme comportant actuellement six themes d’ateliers. Lors de l’inscription, elles s’entretiennent avec l’educateur pour complet...
Published on Dec 7, 2018in Journal of Cosmetic Dermatology1.31
Tomoko Yonezawa13
Estimated H-index: 13
(Okayama University),
Ryusuke Momota10
Estimated H-index: 10
(Okayama University)
+ 6 AuthorsToshitaka Oohashi30
Estimated H-index: 30
(Okayama University)
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