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Socio-economic costs of osteoarthritis: A systematic review of cost-of-illness studies

Published on Apr 1, 2015in Seminars in Arthritis and Rheumatism5.072
· DOI :10.1016/j.semarthrit.2014.10.012
Jaume Puig-Junoy24
Estimated H-index: 24
(UPF: Pompeu Fabra University),
Alba Ruiz Zamora1
Estimated H-index: 1
(UPF: Pompeu Fabra University)
Sources
Abstract
Abstract Objective The burden of illness that can be attributed to osteoarthritis is considerable and ever increasing. The aim of this systematic review is to analyze currently available data derived from cost-of-illness studies on the healthcare and non-healthcare costs of osteoarthritis. Methods PubMed, Index Medicus Espanol (IME), and the Spanish Database of Health Sciences [ Indice Bibliografico Espanol en Ciencias de la Salud (IBECS)] were searched up to the end of April 2013. This study adhered to the PRISMA guidelines. Articles were reviewed and the study quality assessed by two independent investigators with consensus resolution of discrepancies. Results We identified 39 studies that investigated the socio-economic cost of osteoarthritis. Only nine studies took a social perspective. Rather than estimating the incremental cost of osteoarthritis, nine studies estimated the total cost of treating patients with osteoarthritis without a control for comorbidity. The other 30 studies determined the incremental cost with or without a control group. Only nine studies assessed a comprehensive list of healthcare resources. The annual incremental healthcare costs of generalized osteoarthritis ranged from €705 to €19,715. The annual incremental non-healthcare-related costs of generalized osteoarthritis ranged from €432 to €11,956. Conclusions The study concludes that the social cost of osteoarthritis could be between 0.25% and 0.50% of a country׳s GDP. This should be considered in order to foster studies that take into account both healthcare and non-healthcare costs.
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References65
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Last. Nigel K. Arden (University of Oxford)H-Index: 69
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Osteoarthritis (OA) is the most common form of arthritis in the US, and a leading cause of disability. It is typically defined in epidemiologic studies on the basis of radiographic findings and consideration of symptoms. Its incidence and prevalence are rising, likely related to the aging of the population and increasing obesity. Risk factors for OA include a number of person-level factors, such as age, sex, obesity, and genetics, as well as joint-specific factors that are likely reflective of a...
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