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Original paper

Epidemic influenza and vitamin D

Volume: 134, Issue: 6, Pages: 1129 - 1140
Published: Sep 7, 2006
Abstract
In 1981, R. Edgar Hope-Simpson proposed that a ‘seasonal stimulus’ intimately associated with solar radiation explained the remarkable seasonality of epidemic influenza. Solar radiation triggers robust seasonal vitamin D production in the skin; vitamin D deficiency is common in the winter, and activated vitamin D, 1,25(OH) 2 D, a steroid hormone, has profound effects on human immunity. 1,25(OH) 2 D acts as an immune system modulator, preventing...
Paper Details
Title
Epidemic influenza and vitamin D
Published Date
Sep 7, 2006
Volume
134
Issue
6
Pages
1129 - 1140
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