Pachydermoperiostosis: Analysis of the connective tissue abnormality in one family

Background: Pachydermoperiostosis (PDP) is a rare hereditary disease characterized by hyperostosis, clubbing of fingers, coarse skin, and abnormalities in other organs, such as the gastrointestinal tract. Previous studies have disclosed several abnormalities in the connective tissue in these patients. Objective: The purpose of the study was to investigate connective tissue abnormalities in one family with PDP. Methods: Clinical features were...