Insulin resistance is a cellular antioxidant defense mechanism

Volume: 106, Issue: 42, Pages: 17787 - 17792
Published: Oct 20, 2009
Abstract
We know a great deal about the cellular response to starvation via AMPK, but less is known about the reaction to nutrient excess. Insulin resistance may be an appropriate response to nutrient excess, but the cellular sensors that link these parameters remain poorly defined. In the present study we provide evidence that mitochondrial superoxide production is a common feature of many different models of insulin resistance in adipocytes, myotubes,...
Paper Details
Title
Insulin resistance is a cellular antioxidant defense mechanism
Published Date
Oct 20, 2009
Volume
106
Issue
42
Pages
17787 - 17792
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