Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1
Abstract
Apolipoprotein A-I (apoA-I) and an apoA-I peptide mimetic removed seeding molecules from human low density lipoprotein (LDL) and rendered the LDL resistant to oxidation by human artery wall cells. The apoA-I-associated seeding molecules included hydroperoxyoctadecadienoic acid (HPODE) and hydroperoxyeicosatetraenoic acid (HPETE). LDL from mice genetically susceptible to fatty streak lesion formation was highly susceptible to oxidation by artery...
Paper Details
Title
Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1
Published Date
Sep 1, 2000
Journal
Volume
41
Issue
9
Pages
1481 - 1494
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