Optical control of mammalian endogenous transcription and epigenetic states

Nature64.80
Volume: 500, Issue: 7463, Pages: 472 - 476
Published: Jun 2, 2016
Abstract
The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causal gene functions in cellular and organismal processes therefore necessitates approaches that enable spatially and temporally precise modulation of gene expression. Recently, a variety of microbial and plant-derived light-sensitive proteins have been engineered as optogenetic actuators, enabling...
Paper Details
Title
Optical control of mammalian endogenous transcription and epigenetic states
Published Date
Jun 2, 2016
Journal
Volume
500
Issue
7463
Pages
472 - 476
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