Diethyl- and Di-n-Butyltin(IV) 3-Amino-4-Methylbenzoates: Synthesis, Spectroscopic Characterization and in Vitro Antitumor Activity

Diethyl‐ and di‐n‐butyltin(IV) oxides react with 3‐amino‐4‐methylbenzoic acid in a 1:2 ( a ) and 1:1 ( b ) molar ratio to yield dialkyltin compounds of the types R 2 Sn[O 2 C‐C 6 H 3 ‐3‐NH 2 ‐4‐CH 3 ] 2 (a) and {[R 2 Sn(O 2 C‐C 6 H 3 ‐3‐NH 2 ‐4‐CH 3 )] 2 O} 2 ( b ). The compounds obtained were characterized by 1 H, 13 C, 119 Sn NMR and by Mössbauer spectroscopy. Compound 1a was tested in vitro against two human tumor cell lines, MCF‐7, a mammary...