Large Chromosomal Rearrangements during a Long-Term Evolution Experiment with Escherichia coli
Abstract
null Large-scale rearrangements may be important in evolution because they can alter chromosome organization and gene expression in ways not possible through point mutations. In a long-term evolution experiment, twelve Escherichia coli populations have been propagated in a glucose-limited environment for over 25 years. We used whole-genome mapping (optical mapping) combined with genome sequencing and PCR analysis to identify the large-scale...
Paper Details
Title
Large Chromosomal Rearrangements during a Long-Term Evolution Experiment with Escherichia coli
Published Date
Oct 31, 2014
Journal
Volume
5
Issue
5
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