A Search for Variants Associated With Young-Onset Type 2 Diabetes in American Indians in a 100K Genotyping Array

OBJECTIVE— To identify genetic variants in linkage disequilibrium with those conferring diabetes susceptibility, a genome-wide association study for young-onset diabetes was conducted in an American-Indian population. RESEARCH DESIGN AND METHODS— Data come from 300 case subjects with type 2 diabetes with age of onset <25 years and 334 nondiabetic control subjects aged ≥45 years. To provide for tests of within-family association, 121...