Blood Pressure Loci Identified with a Gene-Centric Array
Abstract
Raised blood pressure (BP) is a major risk factor for cardiovascular disease. Previous studies have identified 47 distinct genetic variants robustly associated with BP, but collectively these explain only a few percent of the heritability for BP phenotypes. To find additional BP loci, we used a bespoke gene-centric array to genotype an independent discovery sample of 25,118 individuals that combined hypertensive case-control and general...
Paper Details
Title
Blood Pressure Loci Identified with a Gene-Centric Array
Published Date
Dec 1, 2011
Volume
89
Issue
6
Pages
688 - 700
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