PRSice: Polygenic Risk Score software
Abstract
Summary: A polygenic risk score (PRS) is a sum of trait-associated alleles across many genetic loci, typically weighted by effect sizes estimated from a genome-wide association study. The application of PRS has grown in recent years as their utility for detecting shared genetic aetiology among traits has become appreciated; PRS can also be used to establish the presence of a genetic signal in underpowered studies, to infer the genetic...
Paper Details
Title
PRSice: Polygenic Risk Score software
Published Date
Dec 29, 2014
Journal
Volume
31
Issue
9
Pages
1466 - 1468
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