A method for handling batch-to-batch parametric drift using moving horizon estimation: Application to run-to-run MPC of batch crystallization

In this work, we develop a run-to-run (R2R) model parameter estimation scheme based on moving horizon estimation (MHE) concepts for the modeling of batch-to-batch process model parameter variation using a polynomial regression scheme in a moving horizon fashion. Subsequently, the batch process model parameters computed via the proposed R2R model parameter estimation scheme are used in a model predictive controller (MPC) within each batch to...