Autophagy in the Pathogenesis of Disease
Abstract
Autophagy is a lysosomal degradation pathway that is essential for survival, differentiation, development, and homeostasis. Autophagy principally serves an adaptive role to protect organisms against diverse pathologies, including infections, cancer, neurodegeneration, aging, and heart disease. However, in certain experimental disease settings, the self-cannibalistic or, paradoxically, even the prosurvival functions of autophagy may be...
Paper Details
Title
Autophagy in the Pathogenesis of Disease
Published Date
Jan 1, 2008
Journal
Volume
132
Issue
1
Pages
27 - 42
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Notes
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