Original paper
Emerging landscape of oncogenic signatures across human cancers
Abstract
Chris Sander and colleagues have extracted significant functional events from 12 tumor types. Tumors can be classified as being driven largely by either mutation or copy number changes, and, within this division, subclasses of cross-tissue patterns of events are discerned that suggest sets of combinatorial therapies. Cancer therapy is challenged by the diversity of molecular implementations of oncogenic processes and by the resulting variation...
Paper Details
Title
Emerging landscape of oncogenic signatures across human cancers
Published Date
Sep 26, 2013
Journal
Volume
45
Issue
10
Pages
1127 - 1133
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Notes
History