Simple procedure applying lactose induction and one-step purification for high-yield production of rhCIFN

Volume: 63, Issue: 5, Pages: 708 - 714
Published: Oct 11, 2015
Abstract
Recombinant consensus interferon (CIFN) is a therapeutic protein with molecular weight of 19.5 kDa having broad spectrum antiviral activity. Recombinant human CIFN (rhCIFN) has previously been expressed in Escherichia coli using isopropyl-β-d-thiogalactopyranoside (IPTG), a non-metabolizable and expensive compound, as inducer. For economical and commercial-scale recombinant protein production, it is greatly needed to increase the product yield...
Paper Details
Title
Simple procedure applying lactose induction and one-step purification for high-yield production of rhCIFN
Published Date
Oct 11, 2015
Volume
63
Issue
5
Pages
708 - 714
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