Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis

Volume: 40, Issue: 6, Pages: 2454 - 2469
Published: Mar 1, 2012
Abstract
Alternative splicing (AS) coupled to nonsense-mediated decay (NMD) is a post-transcriptional mechanism for regulating gene expression. We have used a high-resolution AS RT-PCR panel to identify endogenous AS isoforms which increase in abundance when NMD is impaired in the Arabidopsis NMD factor mutants, upf1-5 and upf3-1. Of 270 AS genes (950 transcripts) on the panel, 102 transcripts from 97 genes (32%) were identified as NMD targets....
Paper Details
Title
Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis
Published Date
Mar 1, 2012
Volume
40
Issue
6
Pages
2454 - 2469
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