Molecular basis for D− Japanese: identification of novel DEL and D− alleles

Background and Objectives The occurrence of D − is approximately 0·5% in J apanese, but DEL in apparently D − individuals is relatively common compared with that in C aucasian populations. On the basis of molecular genetics, we examined D − Japanese blood donors. Methods A standard serological technique was used for R h D typing, and we selected 3526 D − blood samples. Genomic DNA obtained from whole blood was used for RHD analysis by polymerase...