Original paper
Belimumab reduces autoantibodies, normalizes low complement levels, and reduces select B cell populations in patients with systemic lupus erythematosus
Abstract
Objective To assess the effects of the B lymphocyte stimulator (BLyS)–specific inhibitor belimumab on immunologic biomarkers, including B cell and T cell populations, and maintenance of antibody titers to prior vaccines in autoantibody‐positive systemic lupus erythematosus (SLE) patients. Methods Pooled data from 2 phase III trials, the Study of Belimumab in Subjects with SLE 52‐week (BLISS‐52) and 76‐week (BLISS‐76) trials, comparing belimumab...
Paper Details
Title
Belimumab reduces autoantibodies, normalizes low complement levels, and reduces select B cell populations in patients with systemic lupus erythematosus
Published Date
Jun 26, 2012
Journal
Volume
64
Issue
7
Pages
2328 - 2337
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Notes
History