Paracetamol (Acetaminophen) in Stroke 2 (PAIS 2): Protocol for a Randomized, Placebo-Controlled, Double-Blind Clinical Trial to Assess the Effect of High-Dose Paracetamol on Functional Outcome in Patients with Acute Stroke and a Body Temperature of 36·5°C or above
Abstract
Rationale In the first hours after stroke onset, subfebrile temperatures and fever have been associated with poor functional outcome. In the first Paracetamol (Acetaminophen) in Stroke trial, a randomized clinical trial of 1400 patients with acute stroke, patients who were treated with high-dose paracetamol showed more improvement on the modified Rankin Scale at three-months than patients treated with placebo, but this difference was not...
Paper Details
Title
Paracetamol (Acetaminophen) in Stroke 2 (PAIS 2): Protocol for a Randomized, Placebo-Controlled, Double-Blind Clinical Trial to Assess the Effect of High-Dose Paracetamol on Functional Outcome in Patients with Acute Stroke and a Body Temperature of 36·5°C or above
Published Date
May 22, 2013
Volume
10
Issue
3
Pages
457 - 462
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