Ultraviolet Photoalteration of Late Na+ Current in Guinea-pig Ventricular Myocytes

Volume: 210, Issue: 1, Pages: 43 - 50
Published: Mar 1, 2006
Abstract
UV irradiation has multiple effects on mammalian cells, including modification of ion channel function. The present study was undertaken to investigate the response of membrane currents in guinea-pig ventricular myocytes to the type A (355, 380 nm) irradiation commonly used in Ca(2+) imaging studies. Myocytes configured for whole-cell voltage clamp were generally held at -80 mV, dialyzed with K(+)-, Na(+)-free pipette solution, and bathed with...
Paper Details
Title
Ultraviolet Photoalteration of Late Na+ Current in Guinea-pig Ventricular Myocytes
Published Date
Mar 1, 2006
Journal
Volume
210
Issue
1
Pages
43 - 50
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