Atorvastatin Effect on Circulating and Leukocyte-Produced CD40 Ligand Concentrations in People with Normal Cholesterol Levels: A Pilot Study

Study Objectives . To investigate whether atorvastatin decreases serum or leukocyte‐produced CD40 ligand (CD40L) levels and whether these effects are dependent on reduction in low‐density lipoprotein cholesterol (LDL) levels in people without overt dyslipidemia. Design . Prospective pilot study. Setting . University research center. Subjects . Twenty‐five normocholesterolemic volunteers (mean age 32 ± 11 yrs; 15 women, 10 men) without...