Mendelian randomization: genetic anchors for causal inference in epidemiological studies

Volume: 23
Published: Sep 15, 2014
Abstract
Observational epidemiological studies are prone to confounding, reverse causation and various biases and have generated findings that have proved to be unreliable indicators of the causal effects of modifiable exposures on disease outcomes. Mendelian randomization (MR) is a method that utilizes genetic variants that are robustly associated with such modifiable exposures to generate more reliable evidence regarding which interventions should...
Paper Details
Title
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
Published Date
Sep 15, 2014
Volume
23
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