Alzheimer's disease: the amyloid cascade hypothesis
Abstract
In both metazoan development and metastatic cancer, migrating cells must carry out a detailed, complex program of sensing cues, binding substrates, and moving their cytoskeletons. The linker cell in Caenorhabditis elegans males undergoes a stereotyped migration that guides gonad organogenesis, occurs with precise timing, and requires the nuclear hormone receptor NHR-67. To better understand how this occurs, we performed RNA-seq of individually...
Paper Details
Title
Alzheimer's disease: the amyloid cascade hypothesis
Published Date
Apr 10, 1992
Journal
Volume
256
Issue
5054
Pages
184 - 185
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