Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn’s disease

Gut24.50
Volume: 57, Issue: 7, Pages: 903 - 910
Published: Jul 1, 2008
Abstract
Background and aims: null Reduced ileal Paneth cell α-defensin expression has been reported to be associated with Crohn’s disease, especially in patients carrying NOD2 mutations. The aim of this study was to independently assess whether NOD2, α-defensins and Crohn’s disease are linked. null Methods: null Using quantitative real-time polymerase chain reaction (RT-PCR), we measured the mRNA expression levels of key Paneth cell antimicrobial...
Paper Details
Title
Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn’s disease
Published Date
Jul 1, 2008
Journal
Volume
57
Issue
7
Pages
903 - 910
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.