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Importance of frailty in patients with cardiovascular disease

Published on Jul 7, 2014in European Heart Journal23.24
· DOI :10.1093/eurheartj/ehu197
Mandeep Singh45
Estimated H-index: 45
(Mayo Clinic),
Ralph Stewart33
Estimated H-index: 33
(Auckland City Hospital),
Harvey D White Mb DSc Facc117
Estimated H-index: 117
(Auckland City Hospital)
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Abstract
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality. With the ageing population, the prognostic determinants among others include frailty, health status, disability, and cognition. These constructs are seldom measured and factored into clinical decision-making or evaluation of the prognosis of these at-risk older adults, especially as it relates to high-risk interventions. Addressing this need effectively requires increased awareness and their recognition by the treating cardiologists, their incorporation into risk prediction models when treating an elderly patient with underlying complex CVD, and timely referral for comprehensive geriatric management. Simple measures such as gait speed, the Fried score, or the Rockwood Clinical Frailty Scale can be used to assess frailty as part of routine care of elderly patients with CVD. This review examines the prevalence and outcomes associated with frailty with special emphasis in patients with CVD.
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  • References (101)
  • Citations (91)
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References101
Newest
Published on Aug 1, 2014in Jacc-Heart Failure8.91
R. Stewart12
Estimated H-index: 12
(University of Auckland),
Dominika Szalewska4
Estimated H-index: 4
(Gdańsk Medical University)
+ 14 AuthorsBenoit Coutu15
Estimated H-index: 15
(UdeM: Université de Montréal)
Abstract Objectives The objective of this study was to assess the prognostic significance of exercise capacity in patients with ischemic left ventricular (LV) dysfunction eligible for coronary artery bypass graft surgery (CABG). Background Poor exercise capacity is associated with mortality, but it is not known how this influences the benefits and risks of CABG compared with medical therapy. Methods In an exploratory analysis, physical activity was assessed by questionnaire and 6-min walk test i...
Published on Apr 1, 2014in Journal of the American College of Cardiology18.64
Ralph Stewart33
Estimated H-index: 33
(Auckland City Hospital),
Dominika Szalewska1
Estimated H-index: 1
(Auckland City Hospital)
+ 14 AuthorsBenoit Coutu1
Estimated H-index: 1
(Auckland City Hospital)
Objective To assess the prognostic significance of exercise capacity in patients with ischemic left ventricular (LV) dysfunction eligible for coronary artery bypass surgery (CABG).
Published on Dec 1, 2013in BMC Medicine8.29
Ian D. Cameron54
Estimated H-index: 54
(USYD: University of Sydney),
Nicola Fairhall12
Estimated H-index: 12
(USYD: University of Sydney)
+ 6 AuthorsSusan Kurrle25
Estimated H-index: 25
Background Frailty is a well known and accepted term to clinicians working with older people. The study aim was to determine whether an intervention could reduce frailty and improve mobility.
Published on Oct 14, 2013in European Heart Journal23.24
Melanie Nichols18
Estimated H-index: 18
(University of Oxford),
Nick Townsend18
Estimated H-index: 18
(University of Oxford)
+ 1 AuthorsMike Rayner47
Estimated H-index: 47
(University of Oxford)
This paper provides an update for 2014 on the burden of cardiovascular disease (CVD), and in particular coronary heart disease (CHD) and stroke, across the countries of Europe. Cardiovascular disease causes more deaths among Europeans than any other condition, and in many countries still causes more than twice as many deaths as cancer. There is clear evidence in most countries with available data that mortality and case-fatality rates from CHD and stroke have decreased substantially over the las...
Published on Oct 14, 2013in European Heart Journal23.24
Melanie Nichols18
Estimated H-index: 18
(BHF: British Heart Foundation),
Nick Townsend18
Estimated H-index: 18
(BHF: British Heart Foundation)
+ 1 AuthorsMike Rayner47
Estimated H-index: 47
(BHF: British Heart Foundation)
Aims Recent decades have seen very large declines in coronary heart disease (CHD) mortality across most of Europe, partly due to declines in risk factors such as smoking. Cardiovascular diseases (predominantly CHD and stroke), remain, however, the main cause of death in most European countries, and many risk factors for CHD, particularly obesity, have been increasing substantially over the same period. It is hypothesized that observed reductions in CHD mortality have occurred largely within olde...
Published on Oct 1, 2013in International Journal of Cardiology3.47
Stephan von Haehling54
Estimated H-index: 54
(Charité),
Stefan D. Anker120
Estimated H-index: 120
(Charité)
+ 2 AuthorsBruno Vellas90
Estimated H-index: 90
(University of Toulouse)
Abstract Frailty is emerging as a syndrome of pre-disability that can identify persons at risk for negative outcomes. Its presence places the individual at risk for rapid deterioration when a major event such as myocardial infarction or hospitalization occurs. In patients with cardiovascular disease, frailty is about three times more prevalent than among elderly persons without. Screening for frailty in heart disease is important not only because of its prognostic value, but also because a varie...
Published on Aug 6, 2013in Circulation23.05
Quinn R. Pack9
Estimated H-index: 9
(Mayo Clinic),
Kashish Goel22
Estimated H-index: 22
(Mayo Clinic)
+ 5 AuthorsRandal J. Thomas27
Estimated H-index: 27
(Mayo Clinic)
Published on Aug 1, 2013in Journal of Nutrition Health & Aging2.66
Bruno Vellas90
Estimated H-index: 90
(University of Toulouse),
L. Balardy1
Estimated H-index: 1
(French Institute of Health and Medical Research)
+ 6 AuthorsMatteo Cesari56
Estimated H-index: 56
The frailty syndrome is a pre-disability condition suitable to be targeted by preventive interventions against disability. In order to identify frail older persons at risk of negative outcomes, general practitioners must be provided with an easy and quick screening tool for detecting frailty without special effort. In the present paper, we present the screening tool for frailty that the Gerontopole of Toulouse (France) has developed and implemented in primary care in the region with the collabor...
Published on Aug 1, 2013in Journal of Aging and Health2.01
Amrit Kanwar4
Estimated H-index: 4
(UW: University of Wisconsin-Madison),
Mandeep Singh45
Estimated H-index: 45
(Mayo Clinic)
+ 3 AuthorsVeronique Lee Roger96
Estimated H-index: 96
(Mayo Clinic)
Objectives: To determine the prevalence and relationship of frailty and health-related quality of life (HRQOL) among residents of long-term care [nursing homes (NH) and assisted living (AL)] facilities. Methods: Residents of NH and AL facilities in La Crosse County, Wisconsin, were recruited 1/2009-6/2010 and assessed for frailty (gait speed, unintended weight loss, grip strength), comorbidity (Charlson index), and HRQOL [Short Form (SF)-36]. Results: Among 137 participants, 85% were frail. Frai...
John E. Morley Mb BCh131
Estimated H-index: 131
(SLU: Saint Louis University),
Bruno Vellas90
Estimated H-index: 90
(French Institute of Health and Medical Research)
+ 17 AuthorsJonathan Evans8
Estimated H-index: 8
Frailty is a clinical state in which there is an increase in an individual's vulnerability for developing increased dependency and/or mortality when exposed to a stressor. Frailty can occur as the result of a range of diseases and medical conditions. A consensus group consisting of delegates from 6 major international, European, and US societies created 4 major consensus points on a specific form of frailty: physical frailty.
Cited By91
Newest
Published on Feb 4, 2019in BMC Geriatrics2.82
Aly Chkeir5
Estimated H-index: 5
(CNRS: Centre national de la recherche scientifique),
Jean-Luc Novella22
Estimated H-index: 22
+ 3 AuthorsJacques Duchêne18
Estimated H-index: 18
(CNRS: Centre national de la recherche scientifique)
Background Frailty detection and remote monitoring are of major importance for slowing down, and/or even stopping the frailty process in home-dwelling older people. Taking the Fried’s criteria as a reference, this work aims to compare the results produced by a technological set (ARPEGE Pack) with those obtained by usual clinical tests, as well as to discuss the ability of the Pack to be used for long-run frailty remote monitoring.
Published on Jan 1, 2019in Journal of Biomedical Semantics1.58
Kristina Doing-Harris (Nuance Communications), Bruce E. Bray15
Estimated H-index: 15
(UofU: University of Utah)
+ 6 AuthorsCharlene R. Weir20
Estimated H-index: 20
(UofU: University of Utah)
Background A Cardiac-centered Frailty Ontology can be an important foundation for using NLP to assess patient frailty. Frailty is an important consideration when making patient treatment decisions, particularly in older adults, those with a cardiac diagnosis, or when major surgery is a consideration. Clinicians often report patient’s frailty in progress notes and other documentation. Frailty is recorded in many different ways in patient records and many different validated frailty-measuring inst...
Published on Sep 4, 2019in Journal of Nuclear Cardiology4.11
Rob S. Beanlands47
Estimated H-index: 47
(U of O: University of Ottawa)
Published on Jun 10, 2019in European Journal of Preventive Cardiology5.64
Alessandra Pratesi4
Estimated H-index: 4
(UniFI: University of Florence),
Samuele Baldasseroni16
Estimated H-index: 16
(UniFI: University of Florence)
+ 7 AuthorsFrancesco Fattirolli13
Estimated H-index: 13
(UniFI: University of Florence)
AimCardiac rehabilitation promotes functional recovery after cardiac events. Our study aimed at evaluating whether, compared to usual care, a home-based exercise programme with monthly reinforcemen...
Published on Aug 26, 2019in The Aging Male2.50
Miri Lutski2
Estimated H-index: 2
(CDC: Centers for Disease Control and Prevention),
Galit Weinstein11
Estimated H-index: 11
(University of Haifa)
+ 1 AuthorsUri Goldbourt64
Estimated H-index: 64
(TAU: Tel Aviv University)
AbstractObjective: We investigated the association between severity of angina pectoris (AP) and subsequent late-life frailty among men with cardiovascular disease (CVD).Method: A subset of 351 men ...
Published on 2019in Heart5.08
Ralph Kwame Akyea1
Estimated H-index: 1
(University of Nottingham),
Joe Kai28
Estimated H-index: 28
(University of Nottingham)
+ 2 AuthorsStephen Weng7
Estimated H-index: 7
(University of Nottingham)
To the Editor Our recently published study using electronic health records from primary care setting in the UK examined low-density lipoprotein cholesterol (LDL-C) reduction among patients initiating statins.1 We are grateful to Dr Taher Modarressi, Dr Dieter Lutjohann, Professor Oliver Weingartner, Dr Tulin Muggleton and Dr Ellis Muggleton for their comments. With regards to the points raised: Suboptimal cholesterol response to initiation of statins and future risk of cardiovascular disease – D...
Published on 2019in European Heart Journal23.24
Philippe Giral45
Estimated H-index: 45
,
A. Neumann7
Estimated H-index: 7
(CNAM: Conservatoire national des arts et métiers)
+ 1 AuthorsJoël Coste2
Estimated H-index: 2
(CNAM: Conservatoire national des arts et métiers)
Published on Jul 14, 2019in European Heart Journal23.24
Thomas F. Lüscher121
Estimated H-index: 121
(Imperial College London)
Published on Jul 3, 2019in Frontiers in Physiology3.20
Izabella Uchmanowicz8
Estimated H-index: 8
,
Jadwiga Nessler12
Estimated H-index: 12
+ 5 AuthorsEwa A. Jankowska34
Estimated H-index: 34
Published on Jul 1, 2019in Ageing Research Reviews10.39
Changfeng Man (Jiangsu University), Shouyan Xiang (Jiangsu University), Yu Fan (Jiangsu University)
Abstract Background Frailty has been identified as a risk factor for mortality in patients with acute coronary syndrome (ACS). This meta-analysis aimed to evaluate the association between frailty and all-cause mortality outcome in patients with ACS. Methods Pubmed and Embase databases were searched up to September 26, 2018 for the observational studies evaluating the association between frailty and all-cause mortality in elderly ACS patients. Outcome measures were in-hospital death, short-term a...