Multifunctional Porous Silicon for Therapeutic Drug Delivery and Imaging

Major challenges in drug formulation are the poor solid state stability of drug molecules, poor dissolution/ solubility and/or poor pharmacokinetic properties (bioavailability), which may lead to unreliable in vitro-in vivo (IVIV) correlation. To improve current therapeutical strategies, novel means to deliver poorly water soluble active pharmaceutical ingredients, as well as to target them to specific sites or cells in the body are needed....