Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk: A Systematic Review and Meta-analysis

Published on Mar 18, 2014in Annals of Internal Medicine19.315
· DOI :10.7326/M13-1788
Rajiv Chowdhury24
Estimated H-index: 24
Rajiv Chowdhury52
Estimated H-index: 52
+ 11 AuthorsEmanuele Di Angelantonio54
Estimated H-index: 54
Primary Funding Source: British Heart Foundation, Medical Research Council, Cambridge National Institute for Health Research Biomedical Research Centre, and Gates Cambridge.
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were 1.06 (CI, 0.86 to 1.30), 1.06 (CI, 0.97 to 1.17), 0.84 (CI, 0.63 to 1.11), 0.94 (CI, 0.84 to 1.06), and 1.05 (CI, 0.76 to 1.44), respectively. There was heterogeneity of the associations among individual circulating fatty acids and coronary disease. In randomized, controlled trials, relative risks for coronary disease were 0.97 (CI, 0.69 to 1.36) for -linolenic, 0.94 (CI, 0.86 to 1.03) for long-chain -3 polyunsaturated, and 0.89 (CI, 0.71 to 1.12) for -6 polyunsaturated fatty acid supplemen...
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