Quantitative study on La3+ influx mediated by sodium-calcium exchanger in human lymphocytes
Abstract
Whether La3+ can enter human peripheral blood lymphocytes by the Na+/Ca2+ exchanger or not and the effect of La3+ on the Na+/Ca2+ exchanger activity are examined by fura-2 technique. And that whether La3+ is sequestered by intracellular organelles (mainly endoplasmic reticulum and mitochondria) is studied by this method. La3+uptake is obviously stimulated by pretreating the cells with ouabain and by removing extracellular Na+, and intracellular...
Paper Details
Title
Quantitative study on La3+ influx mediated by sodium-calcium exchanger in human lymphocytes
Published Date
Jan 1, 2002
Volume
45
Issue
6
Pages
586 - 586
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