Selective effects of zolpidem on human memory functions

Zolpidem is an imidazopyridine hypnotic with preferential binding affnity for the o 1 -benzodiazepine (BZD) receptor. The present double-blind, placebo-controlled study evaluated the effects of orally administered zolpidem (15 mg/70 kg) on specific memory functions in 16 healthy volunteers using a battery of word and picture memory tasks. Relative to placebo, zolpidem significantly impaired memory for material presented after drug administration...