Strikingly Low Circulating CRP Concentrations in Ultramarathon Runners Independent of Markers of Adiposity

Objective— This study was undertaken to evaluate to what extent C-reactive protein (CRP) can be reduced by exercise by examining its circulating concentrations in male ultramarathon runners and to determine if low leptin as a robust circulating marker of fat mass could account for low CRP in such men. Methods and Results— Sixty-seven male ultramarathon runners and 63 sedentary male controls of similar age and body mass index were recruited. CRP...