The dual nature of HDL: Anti-Inflammatory and pro-Inflammatory
Abstract
High density lipoprotein (HDL) has long been considered a protective factor against the development of coronary heart disease. Two important roles of HDL include reverse cholesterol transport (RCT) and the modulation of inflammation. The main protein component of HDL; apolipoprotein A-I (apo A-I) is primarily responsible for RCT. Apo A-I can be damaged by oxidative mechanisms, which reduce the protein's ability to promote RCT. In disease states...
Paper Details
Title
The dual nature of HDL: Anti-Inflammatory and pro-Inflammatory
Published Date
May 6, 2015
Journal
Volume
41
Issue
3
Pages
153 - 159
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