Effects of bioflavonoids on hepatic P450 activities
Abstract
1. The effects of tangeretin, green tea flavonoids, and other flavonoids on 7-ethoxyresorufin-O-deethylase (EROD; 450 1A), 7-pentoxyresorufin-O-dealkylase (PROD; P450 2B), p-nitrophenol hydroxylase (PNPH, P450 2E1), and erythromycin-N-demethylase (ERDM; P450 3A) were examined in induced rat liver microsomes. EROD, PNPH, ERDM, and nifedipine oxidase (NIFO; P450 3A4) were examined in human liver microsomes. 2. All flavonoids tested inhibited EROD...
Paper Details
Title
Effects of bioflavonoids on hepatic P450 activities
Published Date
Jun 1, 1995
Journal
Volume
25
Issue
6
Pages
575 - 584
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