Original paper
Ruthenium Porphyrin Compounds for Photodynamic Therapy of Cancer
Abstract
Five 5,10,15,20-tetra(4-pyridyl)porphyrin (TPP) areneruthenium(II) derivatives and a p-cymeneosmium and two pentamethylcyclopentadienyliridium and -rhodium analogues were prepared and characterized as potential photosensitizing chemotherapeutic agents. The biological effects of all these derivatives were assessed on human melanoma tumor cells, and their cellular uptake and intracellular localization were determined. All molecules, except the...
Paper Details
Title
Ruthenium Porphyrin Compounds for Photodynamic Therapy of Cancer
Published Date
Feb 26, 2008
Volume
51
Issue
6
Pages
1811 - 1816
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Notes
History