A2b Adenosine Receptor Regulates Hyperlipidemia and Atherosclerosis

Volume: 125, Issue: 2, Pages: 354 - 363
Published: Jan 17, 2012
Abstract
Background—The cAMP-elevating A2b adenosine receptor (A2bAR) controls inflammation via its expression in bone marrow cells. Methods and Results—Atherosclerosis induced by a high-fat diet in apolipoprotein E–deficient mice was more pronounced in the absence of the A2bAR. Bone marrow transplantation experiments indicated that A2bAR bone marrow cell signals alone were not sufficient to elicit this effect. Intriguingly, liver expression of the A2bAR...
Paper Details
Title
A2b Adenosine Receptor Regulates Hyperlipidemia and Atherosclerosis
Published Date
Jan 17, 2012
Volume
125
Issue
2
Pages
354 - 363
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