Second-generation PLINK: rising to the challenge of larger and richer datasets
Abstract
PLINK 1 is a widely used open-source C/C++ toolset for genome-wide association studies (GWAS) and research in population genetics. However, the steady accumulation of data from imputation and whole-genome sequencing studies has exposed a strong need for faster and scalable implementations of key functions, such as logistic regression, linkage disequilibrium estimation, and genomic distance evaluation. In addition, GWAS and population-genetic...
Paper Details
Title
Second-generation PLINK: rising to the challenge of larger and richer datasets
Published Date
Feb 25, 2015
Journal
Volume
4
Issue
1
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