Activity of Potent and Selective Host Defense Peptide Mimetics in Mouse Models of Oral Candidiasis

Volume: 58, Issue: 7, Pages: 3820 - 3827
Published: Jul 1, 2014
Abstract
There is a strong need for new broadly active antifungal agents for the treatment of oral candidiasis that not only are active against many species of Candida , including drug-resistant strains, but also evade microbial countermeasures which may lead to resistance. Host defense peptides (HDPs) can provide a foundation for the development of such agents. Toward this end, we have developed fully synthetic, small-molecule, nonpeptide mimetics of...
Paper Details
Title
Activity of Potent and Selective Host Defense Peptide Mimetics in Mouse Models of Oral Candidiasis
Published Date
Jul 1, 2014
Volume
58
Issue
7
Pages
3820 - 3827
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