Review paper
Role of Insulin Resistance in Human Disease
Abstract
Resistance to insulin-stimulated glucose uptake is present in the majority of patients with impaired glucose tolerance (IGT) or non-insulin-dependent diabetes mellitus (NIDDM) and in approximately 25% of nonobese individuals with normal oral glucose tolerance. In these conditions, deterioration of glucose tolerance can only be prevented if the beta-cell is able to increase its insulin secretory response and maintain a state of chronic...
Paper Details
Title
Role of Insulin Resistance in Human Disease
Published Date
Dec 1, 1988
Journal
Volume
37
Issue
12
Pages
1595 - 1607
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