The influence of skeletal muscle on systemic aging and lifespan

Volume: 12, Issue: 6, Pages: 943 - 949
Published: Dec 1, 2013
Abstract
Epidemiological studies in humans suggest that skeletal muscle aging is a risk factor for the development of several age-related diseases such as metabolic syndrome, cancer, Alzheimer's and Parkinson's disease. Here, we review recent studies in mammals and Drosophila highlighting how nutrient- and stress-sensing in skeletal muscle can influence lifespan and overall aging of the organism. In addition to exercise and indirect effects of muscle...
Paper Details
Title
The influence of skeletal muscle on systemic aging and lifespan
Published Date
Dec 1, 2013
Journal
Volume
12
Issue
6
Pages
943 - 949
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