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Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratory evidence for effects with corroborative clinical findings

Published on Dec 1, 2014in BMC Complementary and Alternative Medicine2.48
· DOI :10.1186/1472-6882-14-511
Susan Arentz4
Estimated H-index: 4
(University of Western Sydney),
Jason Abbott23
Estimated H-index: 23
(UNSW: University of New South Wales)
+ 1 AuthorsAlan Bensoussan28
Estimated H-index: 28
(University of Western Sydney)
Abstract
Background Polycystic ovary syndrome (PCOS) is a prevalent, complex endocrine disorder characterised by polycystic ovaries, chronic anovulation and hyperandrogenism leading to symptoms of irregular menstrual cycles, hirsutism, acne and infertility. Evidence based medical management emphasises a multidisciplinary approach for PCOS, as conventional pharmaceutical treatment addresses single symptoms, may be contra-indicated, is often associated with side effects and not effective in some cases. In addition women with PCOS have expressed a strong desire for alternative treatments. This review examines the reproductive endocrine effects in PCOS for an alternative treatment, herbal medicine. The aim of this review was to identify consistent evidence from both pre-clinical and clinical research, to add to the evidence base for herbal medicine in PCOS (and associated oligo/amenorrhoea and hyperandrogenism) and to inform herbal selection in the provision clinical care for these common conditions.
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References108
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#1Ricardo Azziz (Georgia Regents University)H-Index: 65
#2Enrico Carmina (University of Palermo)H-Index: 45
Last.Bulent O. Yildiz (Hacettepe University)H-Index: 26
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#1Amie Steel (UTS: University of Technology, Sydney)H-Index: 15
#2Jon Wardle (UTS: University of Technology, Sydney)H-Index: 14
Last.Jon Adams (UTS: University of Technology, Sydney)H-Index: 34
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#1Nasrin Jalilian (Kermanshah University of Medical Sciences)H-Index: 4
#2Masoud Modarresi (Kermanshah University of Medical Sciences)H-Index: 6
Last.Mohammadreza Bozorgmanesh (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 13
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Cited By18
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#1Sehar Toosy (Lancaster University)
#2Ravinder Sodi (University Hospitals of Morecambe Bay NHS Foundation Trust)H-Index: 5
Last.Joseph M. Pappachan (United Lincolnshire Hospitals NHS Trust)H-Index: 13
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#1Amie Steel (UTS: University of Technology, Sydney)H-Index: 15
#2Erica McIntyre (UTS: University of Technology, Sydney)H-Index: 6
Last.Jane Frawley (UTS: University of Technology, Sydney)H-Index: 11
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