Harnessing Type I and Type III CRISPR-Cas systems for genome editing
Abstract
CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated) systems are widespread in archaea and bacteria, and research on their molecular mechanisms has led to the development of genome-editing techniques based on a few Type II systems. However, there has not been any report on harnessing a Type I or Type III system for genome editing. Here, a method was developed to repurpose both CRISPR-Cas systems for genetic...
Paper Details
Title
Harnessing Type I and Type III CRISPR-Cas systems for genome editing
Published Date
Oct 13, 2015
Journal
Volume
44
Issue
4
Pages
e34 - e34
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