Original paper
Prepubertal chronic ethanol administration alters TTF-1 and Oct-2 expression in the hypothalamus of female rats
Abstract
We found that prolonged administration of ethanol (3 g/kg i.p. at 08:00, once per day) to young female rats starting on postnatal day 24 caused delayed puberty. We further found that prolonged ethanol administration changed the typical hypothalamic expression patterns of TTF-1 and Oct-2 and reduced GnRH mRNA expression. We suggest that these changes may cause the ethanol-induced disturbances in the regulation of GnRH in the hypothalamus and may...
Paper Details
Title
Prepubertal chronic ethanol administration alters TTF-1 and Oct-2 expression in the hypothalamus of female rats
Published Date
May 1, 2005
Journal
Volume
136
Issue
1-2
Pages
262 - 266
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Notes
History